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This cadaveric case study examines an 84-year-old female with a brain mass identified as a primary central nervous system lymphoma (PCNSL), discussing its epidemiology, clinical presentation, diagnosis, and treatment. PCNSL is a rare, aggressive lymphoma that primarily affects immunocompromised individuals, the elderly, and males. Diagnosis involves MRI or CT imaging, tumor biopsy, and lumbar puncture. Symptoms include cognitive changes, seizures, incoordination, headaches, papilledema, weight loss, and fever. While the etiology remains unclear, preventive measures include a healthy lifestyle, regular check-ups, and managing immunosuppressive therapy. Raising awareness of at-risk populations can help improve early diagnosis and intervention.
